How Much Does Allergy Shots (Immunotherapy, annual) Cost?
Allergy shots (allergen immunotherapy) involve regular injections of gradually increasing doses of allergens to build tolerance over time. An annual course typically includes weekly buildup injections followed by monthly maintenance doses to reduce allergic reactions to environmental triggers.
Without Insurance
$1,500
With Insurance
$300
Medicare
$250
National Average
$683
Cost by State
| State | Without Insurance | With Insurance | Medicare |
|---|---|---|---|
| Mississippi | $1,095 | $219 | $182 |
| Arkansas | $1,125 | $225 | $188 |
| West Virginia | $1,125 | $225 | $188 |
| Alabama | $1,170 | $234 | $195 |
| Oklahoma | $1,170 | $234 | $195 |
| Kentucky | $1,275 | $255 | $212 |
| Louisiana | $1,290 | $258 | $215 |
| Iowa | $1,320 | $264 | $220 |
| New Mexico | $1,320 | $264 | $220 |
| South Carolina | $1,320 | $264 | $220 |
| South Dakota | $1,320 | $264 | $220 |
| Kansas | $1,335 | $267 | $222 |
| North Dakota | $1,335 | $267 | $222 |
| Idaho | $1,350 | $270 | $225 |
| Nebraska | $1,350 | $270 | $225 |
| Tennessee | $1,350 | $270 | $225 |
| Indiana | $1,395 | $279 | $232 |
| Missouri | $1,395 | $279 | $232 |
| Utah | $1,395 | $279 | $232 |
| Wyoming | $1,395 | $279 | $232 |
| Georgia | $1,410 | $282 | $235 |
| North Carolina | $1,410 | $282 | $235 |
| Michigan | $1,425 | $285 | $238 |
| Montana | $1,425 | $285 | $238 |
| Arizona | $1,470 | $294 | $245 |
| Ohio | $1,470 | $294 | $245 |
| Wisconsin | $1,470 | $294 | $245 |
| Maine | $1,485 | $297 | $248 |
| Texas | $1,485 | $297 | $248 |
| Florida | $1,515 | $303 | $252 |
| Minnesota | $1,515 | $303 | $252 |
| Illinois | $1,545 | $309 | $258 |
| Pennsylvania | $1,545 | $309 | $258 |
| Delaware | $1,560 | $312 | $260 |
| Nevada | $1,560 | $312 | $260 |
| Vermont | $1,560 | $312 | $260 |
| Virginia | $1,560 | $312 | $260 |
| Colorado | $1,590 | $318 | $265 |
| New Hampshire | $1,590 | $318 | $265 |
| Oregon | $1,590 | $318 | $265 |
| Maryland | $1,650 | $330 | $275 |
| Rhode Island | $1,665 | $333 | $278 |
| Washington | $1,665 | $333 | $278 |
| Connecticut | $1,800 | $360 | $300 |
| New Jersey | $1,800 | $360 | $300 |
| California | $1,965 | $393 | $328 |
| Massachusetts | $1,995 | $399 | $332 |
| Alaska | $2,025 | $405 | $338 |
| New York | $2,025 | $405 | $338 |
| Hawaii | $2,070 | $414 | $345 |
Frequently Asked Questions
How much does allergy shots (immunotherapy, annual) cost without insurance?
The average cost of allergy shots (immunotherapy, annual) without insurance in the United States is $1,500. Costs vary significantly by state.
Does insurance cover allergy shots (immunotherapy, annual)?
Most health insurance plans cover allergy shots (immunotherapy, annual) when medically necessary. With insurance, the average out-of-pocket cost is $300.
Does Medicare cover allergy shots (immunotherapy, annual)?
Medicare Part B typically covers allergy shots (immunotherapy, annual) when ordered by a doctor. The average Medicare-approved amount is $250.
Data sourced from CMS Medicare Provider Utilization and Payment Data 2025. Last updated: 2026-03-01. This information is for educational purposes only and does not constitute medical advice. This website is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.