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How Much Does Chemotherapy Session Cost in South Dakota?

The average cost of chemotherapy session in South Dakota is $8,800 without insurance. With insurance, you can expect to pay around $1,760 — saving 80%.

Without Insurance

$8,800

With Insurance

$1,760

Medicare

$1,320

National Average

$4,500

Cost by City

City Without Insurance With Insurance Medicare
Sioux Falls $9,000 $1,800 $1,350
Rapid City $8,600 $1,720 $1,290

Nearby States

How to Save

  • 1. Ask for the cash/self-pay price — often 40-60% less than the billed price.
  • 2. Compare prices between hospitals and freestanding centers.
  • 3. Check if your insurance covers the procedure and what your copay will be.
  • 4. Ask about payment plans or financial assistance programs.
  • 5. Consider nearby states — prices can vary significantly across state lines.

Data sourced from CMS Medicare Provider Utilization and Payment Data 2025. Last updated: 2026-03-01. This information is for educational purposes only and does not constitute medical advice. This website is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.