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How Much Does Knee Replacement Surgery Cost in Mississippi?

The average cost of knee replacement surgery in Mississippi is $25,500 without insurance. With insurance, you can expect to pay around $7,650 — saving 70%.

Without Insurance

$25,500

With Insurance

$7,650

Medicare

$5,850

National Average

$25,000

Cost by City

City Without Insurance With Insurance Medicare
Jackson $27,000 $8,100 $6,200
Gulfport $24,500 $7,350 $5,600

Nearby States

How to Save

  • 1. Ask for the cash/self-pay price — often 40-60% less than the billed price.
  • 2. Compare prices between hospitals and freestanding centers.
  • 3. Check if your insurance covers the procedure and what your copay will be.
  • 4. Ask about payment plans or financial assistance programs.
  • 5. Consider nearby states — prices can vary significantly across state lines.

Data sourced from CMS Medicare Provider Utilization and Payment Data 2025. Last updated: 2026-03-01. This information is for educational purposes only and does not constitute medical advice. This website is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.