How Much Does Skin Biopsy Cost?
A skin biopsy involves removing a small sample of skin tissue for laboratory examination to diagnose skin conditions including rashes, infections, and skin cancers such as melanoma, basal cell, and squamous cell carcinoma.
Without Insurance
$350
With Insurance
$50
Medicare
$40
National Average
$147
Cost by State
| State | Without Insurance | With Insurance | Medicare |
|---|---|---|---|
| Mississippi | $256 | $37 | $29 |
| Arkansas | $263 | $38 | $30 |
| West Virginia | $263 | $38 | $30 |
| Alabama | $273 | $39 | $31 |
| Oklahoma | $273 | $39 | $31 |
| Kentucky | $298 | $43 | $34 |
| Louisiana | $301 | $43 | $34 |
| Iowa | $308 | $44 | $35 |
| New Mexico | $308 | $44 | $35 |
| South Carolina | $308 | $44 | $35 |
| South Dakota | $308 | $44 | $35 |
| Kansas | $312 | $45 | $36 |
| North Dakota | $312 | $45 | $36 |
| Idaho | $315 | $45 | $36 |
| Nebraska | $315 | $45 | $36 |
| Tennessee | $315 | $45 | $36 |
| Indiana | $326 | $47 | $37 |
| Missouri | $326 | $47 | $37 |
| Utah | $326 | $47 | $37 |
| Wyoming | $326 | $47 | $37 |
| Georgia | $329 | $47 | $38 |
| North Carolina | $329 | $47 | $38 |
| Michigan | $333 | $48 | $38 |
| Montana | $333 | $48 | $38 |
| Arizona | $343 | $49 | $39 |
| Ohio | $343 | $49 | $39 |
| Wisconsin | $343 | $49 | $39 |
| Maine | $347 | $50 | $40 |
| Texas | $347 | $50 | $40 |
| Florida | $354 | $51 | $40 |
| Minnesota | $354 | $51 | $40 |
| Illinois | $361 | $52 | $41 |
| Pennsylvania | $361 | $52 | $41 |
| Delaware | $364 | $52 | $42 |
| Nevada | $364 | $52 | $42 |
| Vermont | $364 | $52 | $42 |
| Virginia | $364 | $52 | $42 |
| Colorado | $371 | $53 | $42 |
| New Hampshire | $371 | $53 | $42 |
| Oregon | $371 | $53 | $42 |
| Maryland | $385 | $55 | $44 |
| Rhode Island | $389 | $56 | $44 |
| Washington | $389 | $56 | $44 |
| Connecticut | $420 | $60 | $48 |
| New Jersey | $420 | $60 | $48 |
| California | $462 | $66 | $53 |
| Massachusetts | $466 | $67 | $53 |
| Alaska | $473 | $68 | $54 |
| New York | $473 | $68 | $54 |
| Hawaii | $483 | $69 | $55 |
Frequently Asked Questions
How much does skin biopsy cost without insurance?
The average cost of skin biopsy without insurance in the United States is $350. Costs vary significantly by state.
Does insurance cover skin biopsy?
Most health insurance plans cover skin biopsy when medically necessary. With insurance, the average out-of-pocket cost is $50.
Does Medicare cover skin biopsy?
Medicare Part B typically covers skin biopsy when ordered by a doctor. The average Medicare-approved amount is $40.
Data sourced from American Academy of Dermatology (AAD) 2025. Last updated: 2026-03-01. This information is for educational purposes only and does not constitute medical advice. This website is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.